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加拿大医学专家:对新冠状肺炎病毒没有特效药和病人免疫反应过度是医学界面临的挑战




(大中报/096.ca讯):根据加拿大国际广播的报道,2月12日周三,来自世界卫生组织的高级专家团队开始了在北京的工作。由加拿大著名的流行病学家布鲁斯•艾尔沃德(Bruce Aylward)领导的专家组的工作重点是更多地了解冠状病毒,加快药物和疫苗的研究,尽快遏制以中国为中心的疫情扩散。

艾尔沃德博士曾参与世界卫生组织应对西非埃博拉疫情的指导工作,在传染病控制方面有丰富经验。这次他和其它10位专家将与中国科学家和公共卫生官员合作,研究控制疫情的方法。

今天你也许关心的话题:

每日新闻2月12日 周三 加拿大名列世界最安全国家二,安省第三名确诊患者痊愈
Tim Hortons:奖励计划拖累销售额 在中国的扩张目标不变
市议会8票赞成、5票反对:万锦市将继续举行10月中国国旗升旗仪式

想要阅读与本文有关的话题?请点击本文末的链接!



新型冠状病毒现在的名称已改为COVID-19。中国官方公布的数字是已经有1,000多人死亡和4万确诊病例。中国境外出现的病例不到400例,其中一人确认死亡。

加拿大到目前为止已经确诊的新型冠状病毒感染者为7人,其中4人在卑诗省,3人在安省。

雷斯(Jerome Leis)博士及其团队上个月在多伦多的Sunnybrook健康科学中心治好了加拿大第一例感染者。这是一位50多岁的男子。雷斯医生说,患者的肺部X光片显示异常,因此确认他已感染冠状肺炎,需住院隔离治疗。开始时,医生担心他的病情恶化,已经准备好输氧。但后来并没有用上。

雷斯博士说,这次疫情最可怕之处,也是令中国医生和医护人员感到最难的,是没有针对这种新病毒的任何特定治疗方法。因此当他们尝试治疗重症患者时,实际是在走钢丝,一方面要找到合适的方法帮助免疫系统战胜病毒,另一方面又要避免引起其他问题。

莱斯还给大家讲述了新冠肺炎与流感的两个主要区别,“就其表现形式而言,新型冠状病毒很像流感。关键的区别是我们没有真正可以用于治疗的抗病毒药”。还有另一个关键领域是,医生需要判断哪些患者最好在家隔离以减少暴露和扩散机率,哪些患者确实需要住院得到更高级别的护理。



对于中国武汉的医院来说,后一点尤其重要,那里的医护人员显然在这方面遇到了问题。在上周公布的武汉市138例住院患者病例中,有四分之一以上需要接受重症监护,多数需要有呼吸机支持。

另一个与流感的区别是人体的免疫反应。麦克马斯特大学另一位研究病毒和人体免疫反应的专家马修·米勒(Matthew Miller)说,通常当某人感染了呼吸道病毒时,患者的免疫系统会开始抵抗并杀死该病毒。但是来自中国早期病例的数据表明,有些感染者病情加重的罪魁祸首包括过度活跃的免疫反应。米勒说,当发生大规模免疫反应时,患者遭受的伤害大过康复,并且呼吸困难等问题可能会加剧。在H1N1流感大流行期间也报告了类似的过度活跃的免疫反应。

他说,在紧密平衡的过程中,一些实验性抗病毒药物靶向炎症蛋白,有助于消除过度的炎症,这些炎症蛋白会导致严重的症状,例如呼吸困难。

现在的好消息是,美国有一位感染者在静脉注射了瑞姆昔韦后,很快康复了。这名患者是华盛顿州一名35岁的男性,他曾访问过武汉。而瑞德昔韦原来是用于对抗其他RNA系列病毒的实验性药物。现在还需要研究这种药物的实际作用到底有多大。




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